| REVIEW ARTICLE |
|
| Year : 2023 | Volume
: 3
| Issue : 2 | Page : 44-48 |
|
|
Fecal microbiota transplantation: Applications and challenges in India
Suranjana Banik1, Balamurugan Ramadass2
1 Department of Anatomy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
2 Center of Excellence for Clinical Microbiome Research, All India Institute of Medical Sciences; Department of Biochemistry, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
Correspondence Address:
Balamurugan Ramadass
Department of Biochemistry, Center of Excellence for Clinical Microbiome Research, All India Institute of Medical Sciences, Bhubaneswar - 751 019, Odisha
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/ghep.ghep_37_22
|
|
|
Fecal Microbiota Transplantation (FMT) involves a noninvasive technique of transferring fecal microbiota in patients from healthy donors. Donors are generally chosen from spouses or relatives, though the anonymous donation is also common. FMT is particularly useful in diseases like recurrent clostridium difficile infection, ulcerative colitis, hepatic encephalopathy, metabolic syndrome, autism spectrum disorders, anxiety, graft versus host disease, multiple sclerosis, multi drug resistance etc. FMT is gradually being adapted in India in the major cities but there are various regulatory challenges. Despite the promising nature of FMT in different pathologies, the different barriers ranging from the selection of a healthy donor, high quality control, uniform protocol maintenance, to ensuring effective mode of administration have to be addressed for FMT to become a widely accepted modality of therapy.
|
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
